News

Pregabalin is a chiral γ-aminobutyric acid (GABA) analog that functions as a calcium channel modulator, clinically indicated for neuropathic pain and as adjunctive therapy for partial-onset seizures. Structurally, Pregabalin is described chemically as (S)-3-(aminomethyl)-5-methylhexanoic acid, a branched aliphatic amino acid bearing an isobutyl side chain at the β-position and an aminomethyl group at the α-position.

Cosperpharm now offers a comprehensive portfolio of key intermediates for Daraxonrasib (RMC-6236), providing one-stop supply chain support for the development of this oral RAS(ON) multiselective inhibitor.

Cosperpharm now offers a comprehensive portfolio of key intermediates for MK-0616 (Enlicitide chloride), providing one-stop supply chain support for generic and innovative drug development of the oral PCSK9 inhibitor.

Cosperpharm offers the complete series of intermediates for Nerandomilast (BI-1015550), covering key building blocks from the core heterocyclic scaffold to the cyclobutylmethanol side chain derivative, providing one-stop supply support for generic and innovative drug development.

Zavegepant (Zavzpret®) is a calcitonin gene-related peptide (CGRP) receptor antagonist approved for the acute treatment of migraine in adults. The synthesis of this complex pharmaceutical agent requires multiple key intermediates, each contributing specific structural elements to the final API.

Finerenone (BAY 94-8862, marketed as Kerendia®) is a first-in-class, non-steroidal mineralocorticoid receptor antagonist (MRA) developed by Bayer for the treatment of chronic kidney disease (CKD) associated with type 2 diabetes.