Boc-Asn-OH

Boc-Asn-OH is a cornerstone protected amino acid reagent widely employed in peptide synthesis, medicinal chemistry, and pharmaceutical research. As an N-Boc-protected asparagine derivative, Boc-Asn-OH enables the incorporation of asparagine residues into synthetic peptides and peptidomimetics through Boc solid-phase peptide synthesis (SPPS) strategies. The Boc protecting group on Boc-Asn-OH is cleaved under mild acidic conditions (e.g., TFA), allowing for orthogonal deprotection and sequential coupling in an orderly manner. Boc-Asn-OH is also utilized in the synthesis of bioactive peptides, pharmaceutical intermediates, and peptide-based drug candidates, serving as a critical reagent for both research-scale and process-scale peptide manufacturing. In quality control contexts, Boc-Asn-OH is characterized by its optical purity and chromatographic profile, making it a valuable reference standard for analytical method development in amino acid and peptide analysis.

 

 

Product Parameters

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Parameter	Specification
Product Name	Boc-Asn-OH
CAS Number	7536-55-2
Molecular Formula	C₉H₁₆N₂O₅
Molecular Weight	232.23 g/mol
Appearance	White  powder / crystalline powder
Melting Point	175 °C (dec.)(lit.)
Boiling Point	374.39 °C (rough estimate)
Density	1.2896 (rough estimate)
Flash Point	245 °C
Refractive Index	−7 ° (C=1, DMF)
Optical Rotation	[α]²⁰/D −7.8 ± 0.5°, c = 2% in DMF
pKa	3.79 ± 0.10 (predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature

Safety Information Summary

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Category	Information
Hazard Symbols	Xn (Harmful)
Risk Codes	R36/37/38: Irritating to eyes, respiratory system, and skin
Safety Statements	S22: Do not breathe dust; S24/25: Avoid contact with skin and eyes
Personal Protection	Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA‘s eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166
Storage Class	11 — Combustible Solids
WGK Germany	3
Transport Classification	Not regulated as hazardous for transport under normal conditions

 

 

Why Cosperpharm?

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When your peptide synthesis campaign or pharmaceutical intermediate production requires reliable Boc-protected amino acids, Cosperpharm delivers Boc-Asn-OH with the analytical rigor and supply chain reliability that researchers and manufacturers demand.

 

Quality you can trust. Every batch of Boc-Asn-OH undergoes comprehensive analytical release testing including HPLC purity verification (≥98.5%), optical rotation confirmation, identity verification by IR, and appearance inspection. Our quality system ensures that the Boc protecting group integrity and L-stereochemistry are preserved — because your peptide sequence fidelity depends on the quality of every building block.

 

Documentation that supports your work. Each shipment includes a Certificate of Analysis (COA) with batch-specific purity data, optical rotation values, and chromatographic traceability. Custom quality agreements, stability summaries, and additional documentation are available upon request for regulated applications.

 

Flexible supply across all scales. Cosperpharm supplies Boc-Asn-OH from research quantities (1g–100g) for peptide synthesis and method development, to kilogram-scale batches for process development and commercial peptide manufacturing. R&D samples ship within 5–7 business days; bulk orders ship within 2–3 weeks.

 

Technical support for your synthetic strategy. Our chemistry team can advise on Boc-SPPS coupling conditions, deprotection protocols, and compatibility with various resin systems — because we understand the nuances of peptide synthesis from extensive experience with protected amino acids.

 

Global reach with transparent pricing. Cosperpharm ships to pharmaceutical companies, CROs, research institutes, and analytical laboratories worldwide, with full customs documentation included. Volume discounts apply at larger scales, and we communicate lead times upfront.

 

Contact Us

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Need Boc-Asn-OH for your next peptide synthesis campaign or pharmaceutical intermediate project? Cosperpharm is ready to supply the quality and documentation you require. Reach out to our team for pricing, availability, or technical questions — we’re here to help you move your project forward