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Kopyrrol
  • KopyrrolKopyrrol

Kopyrrol

Model:55921-65-8
Kopyrrol (CAS 55921-65-8), chemically known as pyrrolidinyl diaminopyrimidine oxide, is a water-soluble hair growth promoter structurally related to minoxidil. The molecule features a pyrimidine core bearing two amino groups and an N-oxide functionality at the 3-position, with a pyrrolidine ring attached at the 6-position.

Kopyrrol is a novel hair growth stimulant that functions as a potassium channel opener, similar in mechanism to minoxidil but with improved water solubility and safety profile. Kopyrrol works by improving blood circulation around hair follicles, delivering essential nutrients and oxygen to the hair root, thereby inhibiting hair loss and promoting hair regrowth. Kopyrrol also acts on the hair follicle cycle, transitioning follicles from the resting phase (telogen) to the growth phase (anagen) and prolonging the anagen phase. Studies have demonstrated that Kopyrrol can reduce serum 5α-reductase, androgen receptor, and dihydrotestosterone levels in animal models, contributing to its anti-hair loss efficacy.


Product Parameters

Parameter

Specification

Product Name

Kopyrrol

CAS Number

55921-65-8

Molecular Formula

C₈H₁₃N₅O

Molecular Weight

195.22 g/mol

Appearance

White to pale white crystalline powder

Melting Point

278 °C (dec.)

Boiling Point

549.3 ± 60.0 °C (predicted)

Density

1.60 g/cm³

pKa

4.89 ± 0.10 (predicted)

Storage Condition

2–8 °C, protected from light, sealed

 

Application

Structurally similar to minoxidil, it is an innovative and clinically proven 100% water-soluble, alcohol-free hair growth promoter.

By improving blood circulation on the skin surface, it provides the required nutrients and oxygen to the hair roots, thereby achieving the effects of inhibiting hair loss, strengthening hair roots, and promoting hair growth. By opening potassium ion channels, it transforms hair follicles from the telogen phase to the anagen phase, and can extend the anagen phase of hair.

 

Mechanism of action

1、It repairs weakened hair follicle cells by supplying the nutrients required for hair growth, and acts on the deep structure of the hair root, thereby increasing the number of hairs in the growth phase.

 

2、Acts on the hair roots, which play a vital role in maintaining a healthy scalp and beautiful hair, via blood circulation. It is often used in hair care products to combat hair loss caused by premature senescence of the hair roots.

 

Contact Us

For water-soluble hair growth actives and cosmetic formulation ingredients, Cosperpharm is your trusted partner. Contact our team today to discuss how Kopyrrol can enhance your anti-hair loss product line.

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