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Building the Foundation: Cosperpharma’s Premium Deoxynucleoside Phosphoramidites

2026-10-15 0 Leave me a message

Product List

Product Name

CAS No.

 

DMT-dA(Bz)-CE-Phosphoramidite

98796-53-3

DMT-dG(iBu)-CE-Phosphoramidite

93183-15-4

DMT-dC(Ac)-CE-Phosphoramidite

154110-40-4

DMT-dT-CE-Phosphoramidite

98796-51-1

DMT-dA(PAc)-CE-Phosphoramidite

110543-74-3

DMT-dG(iPr-PAc)-CE-Phosphoramidite

N/A

 

 

Product Advantages

Superior Coupling Efficiency: Our deoxynucleoside phosphoramidites are manufactured under strict anhydrous conditions, ensuring exceptionally low moisture content. This translates directly to high, reproducible coupling yields, which is critical for synthesizing long oligonucleotides and minimizing the accumulation of truncated failure sequences.

 

Versatile Protecting Group Options: We recognize that different synthetic strategies require different chemistries. Alongside the standard benzoyl (Bz), isobutyryl (iBu), and acetyl (Ac) protecting groups, we offer phenoxyacetyl (PAc) and isopropyl-phenoxyacetyl (iPr-PAc) variants. These alternative protecting groups are designed for faster and milder deprotection protocols, which is particularly advantageous when synthesizing sensitive or modified oligonucleotides.

 

Rigorous Quality Assurance: Every batch undergoes comprehensive analytical testing, including HPLC purity verification and mass spectrometry confirmation. A detailed Certificate of Analysis (COA) is provided to guarantee that our specifications meet the rigorous standards required for both research and commercial applications.

 

Applications

Cosperpharma’s Deoxynucleoside Phosphoramidites are integral to a wide array of molecular biology and therapeutic applications:

 

Next-Generation Sequencing (NGS): Providing the high-fidelity building blocks necessary for constructing accurate sequencing libraries.

 

Diagnostics and PCR: Ideal for producing primers and probes requiring maximum reproducibility and sensitivity.

 

Gene Synthesis and CRISPR: Supporting the robust assembly of synthetic genes and the production of highly specific guide RNAs (gRNAs).

 

Antisense Therapeutics: Serving as the foundational DNA components for developing novel nucleic acid-based medicines.

 

Contact Us

Let Cosperpharma be your trusted partner for your next synthesis project. We invite you to request a detailed specification sheet, explore our latest batch data, or order a sample to evaluate our exceptional quality firsthand. Contact us today to discuss how we can support your specific requirements with competitive pricing and reliable lead times.

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