pentadecan-7-ol is a long-chain secondary fatty alcohol characterized by a fifteen-carbon linear alkyl backbone with a hydroxyl group substituted specifically at the C-7 position . Structurally, this secondary alcohol features a chiral center at carbon-7, flanked by two symmetric heptyl and hexyl chains, forming what is chemically described as hexyl-octyl-carbinol . Unlike linear primary alcohols, this mid-chain hydroxyl placement creates a distinctly hydrophobic molecule with a precise polar headgroup, a structural arrangement that significantly reduces its volatility and influences its ability to interact with lipid bilayers . The molecule exists as a waxy solid at room temperature, with the long saturated chains enabling strong van der Waals interactions that drive high melting points and extremely low water solubility. This inherent amphiphilic asymmetry allows pentadecan-7-ol to function as a membrane disruptor and self-assembling building block, as its geometry can induce phase separation in lipid environments rather than simply dissolving them.
pentadecan-7-ol is a naturally occurring secondary alcohol and a versatile high-purity chemical intermediate utilized in antimicrobial research and advanced material synthesis. Studies have demonstrated that pentadecan-7-ol possesses potent inhibitory effects against Gram-positive pathogens, particularly Listeria monocytogenes, where its specific C-7 hydroxyl position optimizes membrane penetration and lipid bilayer destabilization . Beyond its bioactivity, pentadecan-7-ol serves as a crucial precursor in organic synthesis; its secondary alcohol group can be esterified or etherified to create lubricants and surfactants, while the long alkyl chains make it a valuable building block for designing liquid crystals and self-assembling monolayers . Supplied as a stable solid, pentadecan-7-ol offers distinct handling advantages over liquid isomers, ensuring safer storage and accurate weighing for research applications ranging from antifungal mechanism studies to the development of lipophilic drug delivery excipients.
Product Parameters
Parameter
Specification
Product Name
pentadecan-7-ol
CAS Number
4104-59-0
Molecular Formula
C15H32O
Molecular Weight
228.41 g/mol
Physical Form
Solid
Purity
≥95% (standard grade)
Boiling Point
300.24 °C at 760 mmHg (estimated)
Density
0.8221 g/cm³ (estimated)
pKa (Acid)
15.43 ± 0.20 (Predicted)
Storage Condition
Store at room temperature, sealed, dry
Shelf Life
>2 years if stored properly
Synthetic Route
The synthesis of pentadecan-7-ol can be achieved via Grignard addition. A documented approach for constructing asymmetrical secondary alcohols involves reacting 7-(benzyloxy)heptanal with octylmagnesium bromide in dry diethyl ether under reflux, followed by acidic work-up to yield a protected intermediate that is subsequently deprotected to give the target pentadecan-7-ol . Alternative laboratory routes may involve the reduction of the corresponding ketone (pentadecan-7-one) or cross-coupling of appropriate alkyl fragments. Cosperpharm employs validated purification protocols to ensure removal of ketone byproducts and alkyl halide residuals from such synthetic routes
FAQ
Q1: Is this compound hazardous?
A: pentadecan-7-ol is classified with hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Use in a fume hood with appropriate PPE—gloves, safety goggles, and a lab coat .
Q2: What is the typical lead time?
A: R&D quantities (1g–50g) ship within 5–7 business days. Bulk quantities (100g–25kg) typically ship within 2–3 weeks. Expedited processing is available upon request.
Quality Assurance at Cosperpharm
Each batch undergoes:
● Gas chromatography (GC) – purity ≥97.0%
● Non‑aqueous titration – purity ≥97.0%
● Refractive index – confirmatory analysis
● ¹H NMR – structural verification
● Appearance – colorless to light yellow to light orange clear liquid
A comprehensive COA, MSDS (with full GHS information), and certificate of origin accompany every shipment.
Contact us
Ready to secure pentadecan-7-ol for your antimicrobial screening, surfactant synthesis, or material science research? Cosperpharm streamlines procurement from inquiry to delivery.
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