2-tetradecyl oxyethanol

2-Tetradecyl Oxyethanol (CAS 2136-70-1) is a versatile amphiphilic building block that serves as both a non‑ionic surfactant and a synthetic intermediate. 2-Tetradecyl Oxyethanol is widely employed in nanoparticle synthesis, where its surface‑active properties stabilize colloidal dispersions and control particle size distribution. In addition, 2-Tetradecyl Oxyethanol acts as a solubilizing agent for hydrophobic compounds in aqueous reaction systems, enabling homogeneous conditions for otherwise immiscible organic transformations. Furthermore, 2-Tetradecyl Oxyethanol is used in the preparation of liposomal formulations and lipid‑based delivery systems, as its amphiphilic structure promotes the formation of stable bilayer membranes and facilitates the encapsulation of active pharmaceutical ingredients. With a melting point of 33–34 °C and a boiling point of 330.8 °C at atmospheric pressure, 2-Tetradecyl Oxyethanol is supplied as a white crystalline solid at room temperature, offering excellent handling convenience and long‑term stability under proper storage conditions.

Product Parameters

Why Cosperpharm?

When your nanoparticle formulation, liposomal drug delivery project, or surfactant‑mediated synthesis requires a reliable non‑ionic amphiphile with batch‑to‑batch consistency, Cosperpharm delivers 2-Tetradecyl Oxyethanol with the purity and documentation that research‑intensive customers demand.

Surface activity starts with the right amphiphile. The hydrophilic‑lipophilic balance of 2-Tetradecyl Oxyethanol is critical for stabilizing emulsions, controlling nanoparticle size, and ensuring reproducible liposome formation. Any variation in alkyl chain purity or hydroxyl content will directly affect critical micelle concentration and interfacial behavior. Cosperpharm’s analytical release protocol includes HPLC purity verification (≥98%), melting point confirmation (33–34 °C), water content (Karl Fischer), and identity confirmation — because your colloidal stability depends on the quality of this surfactant.

Documentation that supports your research publications and regulatory filings. Every shipment includes a Certificate of Analysis (COA) with batch‑specific purity and characterization data, a Material Safety Data Sheet (SDS), and customs documentation for international delivery. For customers developing lipid‑based drug delivery systems or surfactant formulations for pharmaceutical applications, Cosperpharm provides DMF‑ready documentation packages, method validation reports, stability data, and custom quality agreements upon request.

Flexible supply across all development stages. Cosperpharm supplies 2-Tetradecyl Oxyethanol from 1g–50g reference quantities for formulation screening and method development, to 100g–500g batches for process validation, to 25kg drums for commercial surfactant applications. R&D samples ship within 5–7 business days; bulk orders ship within 2–3 weeks.

Technical support for the full application range. Our formulation science team can advise on optimal surfactant concentrations for nanoparticle synthesis, compatibility with other excipients in liposomal formulations, and analytical methods for quantifying residual surfactant in final products — because we have worked extensively with this amphiphilic building block across multiple customer applications.

Global reach with transparent pricing. Cosperpharm ships to pharmaceutical manufacturers, CROs, universities, and industrial surfactant formulators worldwide, with full customs documentation included. Volume discounts apply at kilogram scales, and we communicate lead times upfront — no hidden fees, no unexpected delays.

Product Advantages

1. Balanced Non‑Ionic Surfactant Profile

2-Tetradecyl Oxyethanol features a C₁₄H₂₉– lipophilic tail and a compact two‑carbon ethoxyethanol hydrophilic head, delivering a favorable hydrophilic‑lipophilic balance (HLB) for applications requiring moderate surfactant strength without excessive hydrophilicity. Its non‑ionic nature eliminates electrostatic interference with charged biomolecules or nanoparticle surfaces.

2. Versatile Synthetic Intermediate

The terminal primary hydroxyl group of 2-Tetradecyl Oxyethanol serves as a versatile handle for derivatization. It can be readily sulfated to produce anionic surfactants, etherified to adjust HLB, or esterified to form surfactants with tailored properties. The saturated alkyl chain provides oxidative stability not found in unsaturated analogs.

3. Nanoparticle Synthesis and Liposomal Formulations

2-Tetradecyl Oxyethanol is widely used as a surfactant in nanoparticle synthesis, where it stabilizes colloidal dispersions and controls particle size. It is also employed in the preparation of liposomes and other lipid‑based delivery systems, where its amphiphilic structure promotes stable bilayer formation and efficient encapsulation of hydrophobic payloads.

4. High Purity with Full Characterization

Cosperpharm supplies 2-Tetradecyl Oxyethanol at ≥98% purity (HPLC) with full characterization data including melting point, water content, residual solvent analysis, and identity confirmation. Batch‑specific COAs provide complete traceability for research documentation and regulatory submissions.

5. Broad Industrial and Laboratory Utility

2-Tetradecyl Oxyethanol finds application across multiple sectors: as a surfactant in detergent and emulsifier manufacturing; as a solubilizing agent in chemical synthesis; as an emulsifying agent in pharmaceutical topical formulations; and as a wetting agent in various industrial processes.

Storage Conditions

Store 2-Tetradecyl Oxyethanol in a tightly sealed container at 2–8 °C in a clean, dry, well‑ventilated area. Keep the container protected from light and moisture. The compound is stable under recommended storage conditions. Do not store near strong oxidizing agents or sources of ignition.

Shelf life: 2 years when stored at 2–8 °C in a sealed container. Accelerated stability data and long‑term stability summaries are available upon request to support regulatory filings.

Handling precautions: Use in a fume hood where appropriate. Wear chemical‑resistant gloves, safety goggles, and a lab coat. Avoid generating dust. Do not eat, drink or smoke in work areas. After handling, wash hands thoroughly. Refer to the Safety Data Sheet (SDS) for complete safety information.

Contact Us

Ready to secure 2-Tetradecyl Oxyethanol for your next surfactant formulation, nanoparticle synthesis project, or liposome development campaign? Cosperpharm is just an email away. Whether you need R&D samples for formulation screening or bulk quantities for industrial production, our team will provide a competitive quote, confirm availability, and schedule a shipment that meets your timeline. Get in touch today to discuss your requirements — we look forward to supporting your research and manufacturing success.