3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]py rimidin-4-one hydrochloride

3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride is a high‑purity heterocyclic building block that plays a significant role in medicinal chemistry research. The unique structural feature of 3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride lies in its pyrido[1,2-a]pyrimidin‑4‑one core, which provides a rigid, nitrogen‑rich scaffold with multiple points for chemical diversification.

Product Parameters

Why Cosperpharm?

When your medicinal chemistry program requires reliable heterocyclic building blocks with documented purity and traceability, Cosperpharm delivers 3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride with the analytical precision and supply chain reliability that research professionals expect.

Quality assurance you can count on. Every batch of 3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride undergoes analytical release testing including HPLC purity verification (≥98%) and appearance inspection. Each batch is assigned a unique lot number with full traceability from synthesis through final packaging.

Documentation that supports your research. Cosperpharm supplies 3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride with comprehensive Certificates of Analysis (COA) that include batch‑specific purity data. For customers integrating this building block into regulated workflows, custom quality agreements are available upon request.

Flexible supply for every stage. Cosperpharm supplies 3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride from 100 mg to 5 g quantities for hit‑to‑lead medicinal chemistry, to larger batches for process development and preclinical supply. R&D samples typically ship within 5–7 business days.

Technical expertise at your service. Our process chemistry team has extensive experience with pyrido[1,2‑a]pyrimidin‑4‑one chemistry and can advise on synthetic transformations and functionalization strategies.

Global logistics with transparent pricing. Cosperpharm ships to research institutions and pharmaceutical companies worldwide with full customs documentation included.

Product Advantages

 Rigid, Nitrogen‑Rich Heterocyclic Scaffold

3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride features a fused pyrido[1,2-a]pyrimidin-4-one core that provides a conformationally rigid, nitrogen-rich scaffold ideal for interacting with biological targets. This scaffold has been validated in drug discovery programs targeting kinases and other enzyme families.

 Versatile 2‑Chloroethyl Handle for Functionalization

The 2‑chloroethyl substituent at the 3‑position of 3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride serves as a versatile handle for nucleophilic substitution reactions, enabling the introduction of diverse functional groups for SAR exploration.

 9‑Hydroxy Group for Further Derivatization

The 9‑hydroxy substituent in 3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride provides an additional point for alkylation, acylation, or other transformations, expanding the chemical space accessible from this scaffold.

 High‑Purity Research Grade Available

3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride is available at ≥98% purity (HPLC), meeting the quality standards required for sensitive medicinal chemistry applications.

 Recognized Pharmaceutical Intermediate

The pyrido[1,2-a]pyrimidin-4-one scaffold of 3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride has been documented as a key intermediate in the synthesis of pharmaceutical agents targeting various therapeutic areas.

Storage Conditions

Store 3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride in a tightly sealed container. Recommended storage at 20 °C for up to 2 years. Keep away from strong oxidizing agents and moisture.

Handling precautions: Use in a fume hood. Wear chemical‑resistant gloves, safety goggles, and a lab coat. Avoid generating dust. Do not eat, drink, or smoke in work areas. After handling, wash hands thoroughly. Refer to the Safety Data Sheet (SDS) for complete safety information.

Contact Us

Looking for a reliable source of 3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride for your medicinal chemistry program? Cosperpharm is ready to support your project.