3-(4-Methoxyphenoxy)propan-1-amine (CAS 100841-00-7) is a primary amine derivative featuring a 3-aminopropyl ether linkage to a para-methoxyphenyl group. The molecular structure of 3-(4-Methoxyphenoxy)propan-1-amine combines a hydrophilic amine functionality with a hydrophobic methoxy-substituted aromatic ring, connected by a flexible three-carbon spacer.
3-(4-Methoxyphenoxy)propan-1-amine is a key intermediate in the synthesis of pharmacologically active compounds, including PPAR-activating agents and arginase inhibitors, with documented applications in patent literature for cardiovascular disease therapeutics and optically active pharmaceutical intermediates . As an amine-based building block, 3-(4-Methoxyphenoxy)propan-1-amine serves as a crucial precursor for amide bond formation, enabling medicinal chemists to construct diverse compound libraries for drug discovery programs. The flexible three-carbon spacer of 3-(4-Methoxyphenoxy)propan-1-amine allows for optimal positioning of pharmacophoric groups in target-binding sites, while the para-methoxy substituent modulates electronic properties and metabolic stability of the final products. In research applications, 3-(4-Methoxyphenoxy)propan-1-amine is utilized as a synthetic intermediate in the preparation of enzyme inhibitors, receptor modulators, and other biologically active molecules, with its favorable physicochemical properties making it suitable for both medicinal chemistry and material science applications.
Product Parameters
Parameter
Specification
Product Name
3-(4-Methoxyphenoxy)propan-1-amine
CAS Number
100841-00-7
Molecular Formula
C₁₀H₁₅NO₂
Molecular Weight
181.23 g/mol
Boiling Point
304.4 °C at 760 mmHg
Density
1.04 g/cm³
Melting Point
36-37 °C
Storage Condition
Keep in dark place,Sealed in dry,2-8°C
Application
3-(4-Methoxyphenoxy)propan-1-amine can be used as a basic reagent for organic synthesis and a pharmaceutical chemical intermediate, and is mostly used in the preparation of drug molecules and functional organic molecules.
Why Cosperpharm?
When your drug discovery program or intermediate synthesis requires amine building blocks with reliable purity and batch-to-batch consistency, Cosperpharm delivers 3-(4-Methoxyphenoxy)propan-1-amine with the analytical rigor and supply flexibility that pharmaceutical customers demand.
Purity that supports reproducible synthesis. The primary amine functionality of 3-(4-Methoxyphenoxy)propan-1-amine is sensitive to oxidation and moisture, and any degradation products can interfere with downstream coupling reactions. Our analytical release protocol includes HPLC purity verification (≥98%), identity confirmation, and stability assessment—because your synthetic success depends on the quality of this building block.
Documentation that supports regulatory submission. Every shipment includes a Certificate of Analysis (COA) with batch-specific HPLC purity and identity confirmation. Custom quality agreements and stability data are available upon request for customers developing pharmaceutical intermediates or filing regulatory applications.
Flexible supply across all development stages. Cosperpharm supplies 3-(4-Methoxyphenoxy)propan-1-amine from gram-scale R&D quantities for medicinal chemistry screening, to kilogram-scale batches for process validation and commercial intermediate manufacturing. R&D samples ship within 5–7 business days; bulk orders ship within 2–3 weeks.
Global reach with transparent pricing. Cosperpharm ships to pharmaceutical manufacturers, CROs, and research laboratories worldwide, with full customs documentation included. Volume discounts apply at larger scales, and we communicate lead times upfront—no hidden fees, no unexpected delays.
FAQ
Q1: How should this compound be stored?
A: Store 3-(4-Methoxyphenoxy)propan-1-amine at room temperature in a cool, dry place in a tightly sealed container. The compound has a shelf life of 2 years under recommended storage conditions .
Q2: Is 3-(4-Methoxyphenoxy)propan-1-amine hazardous?
A: 3-(4-Methoxyphenoxy)propan-1-amine is classified with H302 (Harmful if swallowed). Use in a fume hood with appropriate PPE—lab coat, safety goggles, and chemical-resistant gloves. Refer to the Safety Data Sheet (SDS) for complete safety information .
Contact Us
Whether you're developing cardiovascular therapeutics or scaling up a pharmaceutical intermediate manufacturing process, Cosperpharm delivers high-quality 3-(4-Methoxyphenoxy)propan-1-amine with the documentation and supply reliability you need. Contact our team today to discuss your requirements.
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