5-methoxy-3-methyl-1-benzofuran-2-carbaldehyde

5-Methoxy-3-methyl-1-benzofuran-2-carbaldehyde (CAS 33038-25-4) is a heterocyclic organic compound belonging to the benzofuran family — a class of fused bicyclic heterocycles consisting of a benzene ring fused to a furan ring . The compound features a methoxy group at the 5-position, a methyl group at the 3-position, and an aldehyde functional group at the 2-position of the benzofuran ring.

In medicinal chemistry, 5-Methoxy-3-methyl-1-benzofuran-2-carbaldehyde serves as a valuable building block for the synthesis of more complex molecules, particularly in the development of new pharmaceuticals and functional materials. Its derivatives have been studied for potential biological activities, including antimicrobial and anticancer properties, with ongoing research exploring its potential as a lead compound for drug development . In biological systems, benzofuran derivatives often interact with molecular targets such as enzymes, receptors, and DNA, leading to the inhibition of enzyme activity, modulation of receptor signaling, or interference with DNA replication and transcription.

Furthermore, 5-Methoxy-3-methyl-1-benzofuran-2-carbaldehyde has demonstrated relevance in diabetes research. Patents (US20120053173A1 and US08436043B2) specifically claim benzofuran derivatives bearing a 5-methoxy-3-methyl substitution pattern as compounds providing superior efficacy for the prophylaxis or treatment of diabetes [9†L16-L25]. The compound is also applicable in the synthesis of dyes, pigments, and other industrial chemicals .

Product Parameters

Why Cosperpharm? – Our Competitive Advantages

Quality Assurance at Cosperpharm

Each batch undergoes:

● Gas chromatography (GC) – purity ≥97.0%

● Non‑aqueous titration – purity ≥97.0%

● Refractive index – confirmatory analysis

● ¹H NMR – structural verification

● Appearance – colorless to light yellow to light orange clear liquid

A comprehensive COA, MSDS (with full GHS information), and certificate of origin accompany every shipment.

Frequently Asked Questions (FAQ)

Q1: What are the primary applications of 5-Methoxy-3-methyl-1-benzofuran-2-carbaldehyde?

A: This compound serves as a building block in organic synthesis, particularly for the development of new pharmaceuticals and materials. Its derivatives are studied for antimicrobial and anticancer properties, and it is also used in the synthesis of dyes, pigments, and industrial chemicals.

Q2: What pharmaceutical relevance does this compound have?

A: Patents claim that benzofuran derivatives bearing the 5-methoxy-3-methyl substitution pattern, including this compound, possess superior efficacy for the prophylaxis or treatment of diabetes. Research is also ongoing into its potential as a lead compound targeting specific enzymes or receptors.

Contact Us

Let‘s discuss how Cosperpharm can support your next synthesis project.Have questions about 5-Methoxy-3-methyl-1-benzofuran-2-carbaldehyde? Our knowledgeable team is ready to assist you with technical information, pricing, or custom synthesis options.