Boc-Alaninol/N-Boc-(S)-2-aminopropanol

Boc-Alaninol is a protected amino alcohol widely utilized in peptide synthesis and medicinal chemistry research. As a chiral building block derived from L-alanine, Boc-Alaninol enables the selective incorporation of alanine-derived fragments into complex peptide sequences and bioactive molecules. The Boc protecting group in Boc-Alaninol ensures stability during multi-step synthesis while permitting facile deprotection when the free amine is required. Additionally, Boc-Alaninol serves as a key intermediate in the synthesis of pharmaceutical agents, including silodosin intermediates, and plays a critical role in the preparation of enantiopure oxazolines, peptidomimetics, and other stereo-specific molecules. The crystalline solid form of Boc-Alaninol ensures compatibility with a wide range of organic synthesis protocols.

Product Parameters

Why Cosperpharm?

When your peptide synthesis campaign or pharmaceutical intermediate procurement requires reliable chiral building blocks, Cosperpharm delivers Boc-Alaninol with the consistency, documentation, and supply flexibility that research and manufacturing customers demand.

Enantiopurity you can trust. The (S)-configuration of Boc-Alaninol is the foundation of its utility in asymmetric synthesis. Any racemization or enantiomeric impurity in this starting material will compromise the stereochemical outcome of your downstream transformations. Our analytical release protocol includes chiral HPLC verification, optical rotation confirmation ([α]²⁰/D −8.6° to −11.5°), and identity confirmation by NMR and IR spectroscopy— because your final product stereochemistry depends on the quality of this building block.

Documentation that supports your research and regulatory needs. Every shipment includes a Certificate of Analysis (COA) with batch-specific purity (GC), optical rotation data, and appearance verification. Custom quality agreements, stability summaries, and additional analytical data are available upon request for customers requiring comprehensive documentation.

Flexible supply across all scales. Cosperpharm supplies Boc-Alaninol from 1g–25g quantities for medicinal chemistry research and peptide synthesis scouting, to 100g–500g batches for process development, to multi-kilogram quantities for commercial manufacturing. R&D samples ship within 5–7 business days; bulk orders ship within 2–3 weeks.

Technical support for your synthetic route. Our process chemistry team can advise on Boc deprotection conditions, hydroxyl group activation strategies, and compatibility with various peptide coupling reagents — because we have worked extensively with this chiral amino alcohol across multiple applications.

Synthetic Route

Boc-Alaninol/N-Boc-(S)-2-aminopropanol can be prepared from L-alanine through sequential steps of esterification, protection, and reduction.

Application Scenarios

Peptide Synthesis

Boc-Alaninol serves as a key building block for incorporating alanine-derived fragments into peptide sequences via solid-phase or solution-phase peptide synthesis.

Asymmetric Synthesis

The enantiopure (S)-configuration of Boc-Alaninol makes it an essential chiral synthon for preparing stereo-specific molecules, including oxazolines and peptidomimetics.

Pharmaceutical Intermediate

Boc-Alaninol is used in the preparation of pharmaceutical agents, including silodosin intermediates and other bioactive molecules.

Drug Discovery Research

In pharmaceutical research, Boc-Alaninol is used to create novel compounds with potential therapeutic effects targeting specific biological pathways.

Biomedical Research

Boc-Alaninol is used as a biochemical reagent and biomaterial for life science research.

Contact Us

Sourcing Boc-Alaninol for your peptide synthesis, pharmaceutical intermediate needs, or asymmetric chemistry research should be straightforward. Cosperpharm makes it simple — reach out today to discuss your requirements.