Fmoc-7-Me-Trp-OH

Fmoc-7-Me-Trp-OH is a specialized Fmoc-protected amino acid building block designed for the introduction of 7-methyl-L-tryptophan residues into peptide sequences via Fmoc solid-phase peptide synthesis (SPPS). Fmoc-7-Me-Trp-OH incorporates the acid-labile Fmoc protecting group at the N-terminus, which can be readily removed under mild basic conditions (typically 20% piperidine in DMF) during standard SPPS protocols. Fmoc-7-Me-Trp-OH is characterized by high purity (≥98.0% to ≥99.5% by HPLC/Chiral HPLC) and is supplied as a white to off-white crystalline powder. Fmoc-7-Me-Trp-OH serves as a critical tool for medicinal chemists and peptide researchers developing novel peptide therapeutics with enhanced pharmacological properties, including improved metabolic stability and targeted delivery.

Product Parameters

Why Cosperpharm?

When your peptide synthesis campaign demands high-purity Fmoc-protected amino acids with rigorous analytical characterization, Cosperpharm delivers Fmoc-7-Me-Trp-OH with the quality assurance and supply flexibility that pharmaceutical and biotech researchers require.

Purity that matters for peptide synthesis. The incorporation of non-natural amino acids like 7-methyl-L-tryptophan requires starting materials of exceptional purity to avoid sequence deletions, premature termination, and side-product formation during SPPS. Our Fmoc-7-Me-Trp-OH is released with HPLC purity verification (≥98.0% to ≥99.5% depending on grade), chiral HPLC analysis for enantiomeric purity, and full characterization data including NMR and mass spectrometry.

Documentation to support your research and regulatory needs. Every shipment includes a Certificate of Analysis (COA) with batch-specific purity data, chromatographic traceability, and analytical test results. Custom quality agreements and stability summaries are available upon request for customers with regulatory filing requirements.

Flexible supply from R&D to production. Cosperpharm supplies Fmoc-7-Me-Trp-OH across the full range of applications—from gram-scale quantities for peptide library screening and medicinal chemistry research, to kilogram-scale batches for process development and commercial peptide manufacturing. R&D samples ship within 5–7 business days; bulk orders are available upon request.

Technical support for peptide chemists. Our team understands the nuances of Fmoc SPPS and can provide guidance on coupling conditions, deprotection protocols, and compatibility with various resin systems—because we have extensive experience with this and other Fmoc-amino acid derivatives.

Global reach with transparent pricing. Cosperpharm ships to pharmaceutical companies, CROs, and research institutions worldwide, with full customs documentation included. We communicate lead times upfront—no hidden fees, no unexpected delays.

Application

N-fluoromethoxycarbonyl-7-azatryptophan is a tryptophan derivative that appears as white crystals or crystalline powder. This compound serves as the fundamental building block for peptide drugs; introducing non-natural amino acids into peptide drugs significantly enhances their stability, improves blood-brain barrier penetration, and reduces toxicity. Consequently, the development of novel multifunctional non-natural amino acid blocks plays a crucial role in the research and development of peptide drugs.

Product Quality Assurance

Cosperpharm has established a comprehensive quality assurance system for Fmoc-7-Me-Trp-OH that meets the rigorous expectations of peptide synthesis and pharmaceutical research:

Thorough analytical characterization. Each batch undergoes multi-technique analytical release testing: HPLC purity verification (≥98.0% to ≥99.5% depending on grade), chiral HPLC analysis for enantiomeric purity, appearance verification (white to off-white crystalline powder), and identity confirmation via NMR and mass spectrometry.

Full batch traceability with retention samples. From raw material procurement through synthesis, purification, drying, and final packaging, every step is fully documented and traceable. Each batch receives a unique lot number with sufficient retention samples maintained in accordance with Cosperpharm quality procedures.

Stability monitoring program. Cosperpharm conducts stability studies under recommended storage conditions (2–8 °C, protected from moisture). Stability summaries are available to support customer research and regulatory submissions.

Documentation ready for regulatory submission. Every shipment includes a Certificate of Analysis (COA) with batch-specific purity and characterization data. For customers preparing regulatory filings, Cosperpharm provides custom quality agreements and additional documentation upon request.

Customer-initiated quality audits. Qualified customers are welcome to audit Cosperpharm’s manufacturing, quality control, and documentation facilities. Please contact our regulatory team to schedule an audit.

Contact Us

Ready to secure Fmoc-7-Me-Trp-OH for your next peptide synthesis project or drug discovery campaign? Cosperpharm is here to help. Whether you need a few grams for medicinal chemistry research or kilogram quantities for process development, we provide the quality, documentation, and supply reliability you can count on. Reach out to our team today—we look forward to supporting your research and manufacturing needs.