Sulfachloropyridazine Sodium

Sulfachloropyridazine Sodium is a pivotal veterinary antibiotic, analytical reference standard, and pharmaceutical intermediate with extensive applications across the animal health industry. As a sodium salt, Sulfachloropyridazine Sodium exhibits excellent water solubility, enabling flexible administration routes including oral, intravenous, and intramuscular delivery. In veterinary medicine, Sulfachloropyridazine Sodium is indicated for the treatment of various bacterial infections in food-producing animals, including colibacillosis in calves and swine, fowl cholera, pullorum disease, and coccidiosis in poultry. As an analytical reference standard, Sulfachloropyridazine Sodium is essential for quality control applications in veterinary pharmaceutical manufacturing, method validation, and residue analysis in food products. The versatility of Sulfachloropyridazine Sodium extends to its role in combination therapies with other antimicrobial agents for enhanced efficacy.

Product Parameters

Pharmacological A ction

Its antibacterial spectrum is similar to that of sulfamethoxazole, although its antibacterial activity is slightly weaker than that of sulfamethoxazole. It inhibits the synthesis of microbial tetrahydrofolate and exhibits broad-spectrum antibacterial activity, effective against both Gram-positive and Gram-negative bacteria. The peak plasma concentration is achieved within 1–3 hours after oral administration. This is a sulfonamide-class antibiotic indicated for the treatment of Escherichia coli and Pasteurella infections in livestock and poultry (e.g., pigs, chickens).

Application

Inhibits the synthesis of microbial tetrahydrofolate; exhibits broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria. The peak plasma concentration is achieved within 1–3 hours after oral administration. Sulfonamides – indicated for the treatment of Escherichia coli and Pasteurella infections in livestock and poultry (e.g., pigs, chickens).

FAQ

Q1: What is Sulfachloropyridazine Sodium used for?

A: Sulfachloropyridazine Sodium is primarily used as a veterinary antibiotic for the treatment of bacterial infections in food-producing animals. Indications include colibacillosis in calves and swine, fowl cholera, pullorum disease, coryza, enteritis, and coccidiosis in poultry. It is also used as an analytical reference standard for pharmaceutical quality control and residue analysis.

Q2: What is the mechanism of action of Sulfachloropyridazine Sodium?

A: Sulfachloropyridazine Sodium acts as a competitive inhibitor of bacterial dihydropteroate synthase, an enzyme essential for bacterial folate synthesis. By mimicking para-aminobenzoic acid (PABA), the compound competes for the enzyme's active site, inhibiting folate production and consequently bacterial growth.

Contact Us

Whether you are manufacturing veterinary pharmaceuticals, developing analytical methods for sulfonamide residue testing, or establishing quality control protocols for veterinary drug products, Cosperpharm is your trusted partner for high-quality Sulfachloropyridazine Sodium. Reach out to our team today to discuss your requirements, request a quotation, or learn more about our quality documentation and technical support capabilities.