Sulfanilamide is a pivotal pharmaceutical intermediate, analytical reagent, and certified reference standard with extensive applications across the pharmaceutical and biochemical industries. As the parent compound of the sulfonamide class, Sulfanilamide serves as the key synthetic intermediate for numerous sulfonamide drugs including sulfadiazine, sulfamethoxazole, and sulfathiazole. In analytical chemistry, Sulfanilamide is widely used as a reagent for the determination of nitrite ions, and its reference standard grade is essential for quality control and quantitative analysis in pharmaceutical laboratories. The versatility of Sulfanilamide extends to veterinary medicine, where it is used as a topical antibacterial agent for wound infections caused by susceptible strains of Streptococcus and Staphylococcus.
|
Parameter |
Specification |
|
Product Name |
Sulfanilamide |
|
CAS Number |
63-74-1 |
|
Molecular Formula |
C₆H₈N₂O₂S |
|
Molecular Weight |
172.21 g/mol |
|
Appearance |
White to off-white crystalline powder |
|
Melting Point |
|
|
Boiling Point |
400.5 ± 47.0 °C (lit.) |
|
Density |
1.08 g/cm³ |
|
pKa |
|
|
Storage Condition |
2 - 8 °C |
This medication has relatively low toxicity and can be administered to infants, pregnant or postpartum women, and individuals during their menstrual period; however, it should not be taken in large doses. It is effective against hemolytic streptococcal infections (e.g., erysipelas, pyoderma, tonsillitis) and urinary tract infections (e.g., gonorrhea); it also serves as an intermediate in the synthesis of other sulfonamide drugs (e.g., sulfamethazine, sulfamethoxazole, etc.).
This compound is prepared by chlorosulfonation, amination, hydrolysis, and neutralization of acetanilide. Raw material consumption quotas: acetanilide (99%) – 1032 kg/t; chlorosulfuric acid (96%) – 4521 kg/t; liquid ammonia (99.8%) – 535 kg/t; liquid alkali (30%) – 863 kg/t.
Packaging must be intact; handle with care and place on a level surface; store in a well-ventilated warehouse, away from open flames, high temperatures, and oxidizing agents.
Whether you are manufacturing sulfonamide pharmaceuticals, developing analytical methods for nitrite detection, or establishing quality control protocols for sulfonamide drug products, Cosperpharm is your reliable partner for high-purity Sulfanilamide. Reach out to our team today to discuss your requirements, request a quotation, or learn more about our quality documentation and technical support capabilities.
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