2-((tert-Butoxycarbonyl)amino)-3,3-dicyclopropylpropanoic acid (CAS 2272861-72-8) is an N-Boc-protected amino acid derivative featuring the distinctive 3,3-dicyclopropyl-substituted alanine scaffold. The molecular structure comprises an N-terminal tert-butoxycarbonyl (Boc) protecting group, a carboxylic acid at the C-terminus, and a geminal dicyclopropyl substitution at the β-position.
2-((tert-Butoxycarbonyl)amino)-3,3-dicyclopropylpropanoic acid is a Boc-protected non-natural amino acid building block for pharmaceutical research and development. As the racemic or non-enantiopure version of the dicyclopropylalanine scaffold, 2-((tert-Butoxycarbonyl)amino)-3,3-dicyclopropylpropanoic acid offers researchers a cost-effective entry point for exploring the biological activity of dicyclopropylalanine-containing compounds. The Boc protecting group enables orthogonal deprotection under mild acidic conditions, making 2-((tert-Butoxycarbonyl)amino)-3,3-dicyclopropylpropanoic acid compatible with a wide range of synthetic protocols. The geminal dicyclopropyl substitution at the β-position introduces significant steric bulk and conformational rigidity, properties that have been shown to deliver potent and metabolically stable compounds in drug discovery programs. For researchers requiring defined stereochemistry, the (S)-enantiomer (CAS 2548967-22-0) is also available from Cosperpharm.
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R&D samples: one week; commercial orders: 1–2 months after payment. Express (DHL/FedEx) or air/sea freight available.
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Licensed Exporter
Valid drug import/export license — no compliance delays.
Dual Quality Grades
Both research/pharma grade(≥98%)and high-purity impurity grade(≥99%)available to meet diverse customer needs.
Quality Assurance at Cosperpharm
Each batch undergoes:
Gas chromatography (GC) – purity ≥97.0%
Non‑aqueous titration – purity ≥97.0%
Refractive index – confirmatory analysis
¹H NMR – structural verification
Appearance – colorless to light yellow to light orange clear liquid
A comprehensive COA, MSDS (with full GHS information), and certificate of origin accompany every shipment.
Storage Conditions
Store 2-((tert-Butoxycarbonyl)amino)-3,3-dicyclopropylpropanoic acid in a tightly sealed container at 2–8°C. Keep the container dry, protected from moisture, and stored in a clean, well-ventilated area away from strong oxidizing agents and sources of ignition.
Handling precautions: Use in a fume hood. Wear chemical‑resistant gloves, safety goggles, and a lab coat. Avoid generating dust or aerosols. Do not eat, drink or smoke in work areas. After handling, wash hands thoroughly.
Contact Us
Interested in 2-((tert-Butoxycarbonyl)amino)-3,3-dicyclopropylpropanoic acid for your research program? Reach out to Cosperpharm today — our team is ready to provide pricing, availability, and technical support to accelerate your drug discovery efforts.
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