Boc-Glu-OBzl

Boc-Glu-OBzl is a fundamental amino acid building block widely employed in solid-phase peptide synthesis (SPPS) for the construction of peptides and peptide-based therapeutics. Boc-Glu-OBzl has been extensively used in the synthesis of peptide-based inhibitors targeting human caspases and human rhinovirus (HRV) 3C protease, both of which demonstrate enzyme inhibitory activity in vitro. Additionally, Boc-Glu-OBzl serves as a standard substrate for Vitamin K-dependent carboxylation assays, reflecting its utility in biochemical research applications. As a selectively protected glutamate derivative, Boc-Glu-OBzl enables researchers to introduce glutamate benzyl ester residues into peptides with precision, facilitating the study of protein interactions and the development of novel therapeutic agents.

Product Parameters

Quality that protects your synthesis. The orthogonal protecting groups on Boc-Glu-OBzl are the foundation of your peptide assembly strategy — any impurity in this building block will compromise coupling efficiency and final product purity. Our analytical release protocol includes HPLC purity verification (≥98%), optical rotation confirmation, identity verification by IR, and solubility testing. Every batch is tested to ensure it meets the rigorous demands of Boc SPPS.

Documentation that supports your research and regulatory needs. Every shipment includes a Certificate of Analysis (COA) with batch-specific purity data, optical rotation, and chromatographic traceability. For customers developing peptide-based therapeutics, Cosperpharm provides DMF-ready documentation, stability summaries, and custom quality agreements upon request.

Flexible supply from discovery to production. Cosperpharm supplies Boc-Glu-OBzl across the full range of applications — from gram-scale quantities for medicinal chemistry research and peptide library synthesis, to kilogram-scale batches for preclinical and commercial peptide manufacturing. R&D samples ship within 5–7 business days; bulk orders ship within 2–3 weeks.

Technical expertise in peptide chemistry. Our team understands the nuances of Boc SPPS, including the compatibility of the benzyl ester with various deprotection and cleavage conditions. We can advise on handling protocols, storage optimization, and troubleshooting coupling reactions involving glutamate residues.

Global reach with transparent pricing. Cosperpharm ships to pharmaceutical companies, CROs, and academic research institutions worldwide, with full customs documentation included. Volume discounts apply at larger scales, and we communicate lead times upfront — no hidden fees, no unexpected delays.

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