(2S)-2-aMino-6-((1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethoxy)carbonylaMino)hexanoic acid

(2S)-2-amino-6-((1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethoxy)carbonylamino)hexanoic acid serves as a specialized research tool for chemical biology and protein engineering applications. This photocaged lysine derivative allows researchers to introduce a "caged" lysine residue into proteins or peptides, where the ε-amino group is temporarily blocked until activated by light. The synthesis of (2S)-2-amino-6-((1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethoxy)carbonylamino)hexanoic acid typically involves the reaction of 5-chloromethyl-6-nitrobenzo[d][1,3]dioxole with L-lysine under specific conditions. The nitrobenzodioxole photolabile group can be efficiently removed upon UV irradiation, releasing the free lysine and restoring its native biological function. (2S)-2-amino-6-((1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethoxy)carbonylamino)hexanoic acid is commonly supplied as a solid powder with purity ≥95% and is intended for research use only, not for human therapeutic applications.

 

Product Parameters

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Parameter	Specification
Product Name	(2S)-2-amino-6-((1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethoxy)carbonylamino)hexanoic acid
CAS Number	1221189-11-2
Molecular Formula	C₁₆H₂₁N₃O₈
Molecular Weight	383.35 g/mol
Physical Form	Solid
Density	1.406 ± 0.06 g/cm³ (predicted)
Boiling Point	633.3 ± 55.0 °C
Storage Condition	-20℃

 

Why Cosperpharm?

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When your chemical biology research demands precision and reliability, Cosperpharm delivers (2S)-2-amino-6-((1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethoxy)carbonylamino)hexanoic acid with the quality and service that researchers trust.

 

Photocaged precision for your experiments. The nitrobenzodioxole photolabile group in (2S)-2-amino-6-((1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethoxy)carbonylamino)hexanoic acid must maintain its integrity until the moment of photoactivation. Any degradation or impurity in this photocaged amino acid can compromise the spatiotemporal control of your biological experiments. Our analytical release protocol ensures ≥95% purity with rigorous quality control.

 

Documentation for research compliance. Every shipment includes a Certificate of Analysis (COA) with batch-specific purity data and characterization. Custom quality documentation is available upon request for your research records.

 

Flexible supply for all research scales. Cosperpharm supplies (2S)-2-amino-6-((1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethoxy)carbonylamino)hexanoic acid across a range of quantities to support your research needs.

 

Technical support for photocaging applications. Our team understands the unique requirements of working with photolabile compounds and can provide guidance on storage, handling, and photoactivation conditions.

 

Global reach with transparent pricing. Cosperpharm ships to research institutions and biotechnology companies worldwide with full documentation included.

 

Product Advantages

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Photocaged Amino Acid for Spatiotemporal Control

(2S)-2-amino-6-((1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethoxy)carbonylamino)hexanoic acid functions as a photo-responsive unnatural amino acid (UAA) that enables precise spatiotemporal control of biological processes. The photolabile nitrobenzodioxole group can be cleaved upon exposure to specific wavelengths of light, releasing the active lysine at the desired time and location.

 

 L-Lysine Scaffold with Site-Specific Caging

The compound preserves the native L-lysine stereochemistry (2S configuration), ensuring that upon deprotection, the released lysine maintains its biological activity and can be incorporated into proteins and peptides without disrupting native function.

 

 Stable and Handleable Solid Form

(2S)-2-amino-6-((1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethoxy)carbonylamino)hexanoic acid is supplied as a solid powder that can be conveniently weighed and handled under standard laboratory conditions with appropriate light protection.

 

 Versatile Research Tool

This photocaged amino acid serves as a valuable tool for studying protein function, enzyme mechanisms, signal transduction pathways, and other dynamic biological processes where temporal control of amino acid availability is critical.

 

 Research-Grade Quality

Supplied with ≥95% purity, this compound meets the quality standards required for advanced chemical biology and protein engineering applications.

 

 FAQ

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Q1: What is the primary application of this compound?

A: (2S)-2-amino-6-((1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethoxy)carbonylamino)hexanoic acid is a photocaged lysine derivative used as a photo-responsive unnatural amino acid (UAA) for spatiotemporal control of biological molecules or processes. It enables researchers to "cage" lysine residues and release them upon light activation.

 

Q2: What does "photocaged" mean in this context?

A: "Photocaged" refers to the presence of a photolabile protecting group (the 6-nitrobenzo[d][1,3]dioxole moiety) that masks the ε-amino group of lysine. This protecting group can be cleaved upon exposure to specific wavelengths of light, releasing the free lysine and restoring its biological function.

 

Contact Us

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Sourcing (2S)-2-amino-6-((1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethoxy)carbonylamino)hexanoic acid for your photocaging research shouldn't be complicated. Cosperpharm makes it simple with reliable quality and responsive service.