A-11

A-11 is a lipid compound with two distinct documented identities in the scientific literature. According to MedChemExpress and PeptideDB, A-11 is an ionizable cationic lipid (Compound A-11, also designated CICL1) with a molecular formula of C55H100N2O14 and a molecular weight of 1013.39 g/mol. In this context, A-11 can be used to prepare lipid nanoparticles and has been applied in research involving T cell‑targeted transfection of nucleic acids, as documented in patent WO2022125620A1 (2022). As a synthetic ionizable lipid, A-11 can be stored at 4°C in sealed containers away from moisture and light, with extended stability at –80°C for up to 6 months when prepared as a solution.

Product Parameters

Why Cosperpharm?

Cosperpharm provides A-11 with full transparency regarding its documented literature references and analytical specifications. Recognizing that CAS 2996998-09-3 is associated with distinct chemical entities in the literature, we provide comprehensive batch‑specific documentation — including molecular formula verification and purity data — to help researchers confirm the identity of the material they receive. Our technical support team is available to discuss the specific source and intended application of A-11 for your project, and we can provide additional characterization data (NMR, mass spectrometry) upon request for qualified customers. Cosperpharm ships A-11 globally with standard lead times of 5–7 business days for research quantities, supported by full customs documentation.

Synthetic Route

Published synthetic information specific to A-11 is not available in the open literature. The compound is described in patent WO2022125620A1 (Antibacterial Agents, 2022) as a component for antibacterial formulations, suggesting a synthetic origin for this material. For the lipid A‑type material, the compound is isolated from gram‑negative bacterial sources as the native lipid component of lipopolysaccharide. Cosperpharm supplies A-11 as a research‑grade product with batch‑specific documentation. For customers requiring custom synthesis or process development, please contact our technical team.

Storage Conditions

Store A-11 at 4°C in a tightly sealed container, protected from moisture and light. For extended storage of prepared solutions, store at –80°C for up to 6 months or at –20°C for up to 1 month in sealed containers. Protect from moisture and light during all handling and storage. Allow the sealed container to equilibrate to ambient temperature before opening to minimize moisture condensation. The compound is shipped at room temperature and is stable under ambient conditions for several days during transit.

Handling precautions: Use appropriate personal protective equipment (lab coat, safety goggles, chemical‑resistant gloves) when handling A-11. Work in a well‑ventilated area or fume hood. Avoid skin and eye contact. In case of contact, rinse immediately with plenty of water and seek medical advice if irritation persists. Do not eat, drink, or smoke in work areas. Wash hands thoroughly after handling.