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Lanthanum Carbonate

Lanthanum Carbonate

Lanthanum Carbonate is an inorganic phosphate-binding compound consisting of lanthanum(III) cations and carbonate anions, typically existing as the octahydrate salt. The molecule of Lanthanum Carbonate functions as a non-calcium, non-aluminium phosphate binder that dissociates in the acidic environment of the upper gastrointestinal tract, releasing lanthanum ions that bind dietary phosphate to form insoluble lanthanum phosphate complexes.
Pazopanib Hydrochloride

Pazopanib Hydrochloride

Pazopanib Hydrochloride is a potent, multi-targeted receptor tyrosine kinase inhibitor, formulated as the hydrochloride salt to enhance pharmaceutical properties. Structurally, Pazopanib Hydrochloride consists of a pyrimidine-2,4-diamine core with a 2,3-dimethyl-2H-indazol-6-yl substituent via a methylamino linker, and a 2-methylbenzenesulfonamide group at the 5-position.
Ticagrelor

Ticagrelor

Ticagrelor is the first reversibly binding oral P2Y₁₂ platelet receptor antagonist, featuring a complex cyclopentane-triazolopyrimidine structure with multiple stereocentres. Structurally, Ticagrelor consists of a triazolo[4,5-d]pyrimidine core with a propylthio substituent at the 5-position, a cyclopropylamino group at the 7-position, and a cyclopentane ring bearing three hydroxyl groups and a hydroxyethoxy substituent.
Regorafenib

Regorafenib

Regorafenib Monohydrate is an oral multi-kinase inhibitor that targets angiogenic, stromal, and oncogenic receptor tyrosine kinases. Structurally, Regorafenib Monohydrate consists of a 4-phenoxy-N-methylpicolinamide core with a urea linkage connecting to a 4-chloro-3-(trifluoromethyl)phenyl group, and a fluorine substituent on the central phenyl ring.
Raltitrexed

Raltitrexed

Raltitrexed is a potent and specific thymidylate synthase (TS) inhibitor, belonging to the quinazoline folate analogue class of antineoplastic agents. Structurally, Raltitrexed consists of a 2-methyl-4-oxo-quinazoline ring system linked via a methyl-methylamino bridge to a thiophene ring, which is further connected to a glutamic acid moiety through a carboxamide linkage.
Aprepitant

Aprepitant

Aprepitant is a selective high-affinity antagonist of the human substance P/neurokinin 1 (NK₁) receptor, featuring a complex morpholine core with three stereocenters that define its pharmacological activity. The molecule consists of a 1,2,4-triazol-3-one ring linked via a methylene bridge to a 2,3-disubstituted morpholine ring, which carries a 4-fluorophenyl group and a chiral 1-[3,5-bis(trifluoromethyl)phenyl]ethoxy substituent.
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