Methylene Blue Hydrate

Methylene Blue Hydrate (Methylthioninium chloride hydrate) is a cationic thiazine dye with diverse biological activities. Methylene Blue Hydrate inhibits the catalytic function of inducible and constitutive nitric oxide synthases via oxidation of enzyme-bound ferrous iron. As a pharmaceutical agent, Methylene Blue Hydrate is used as a vasopressor agent and as a diagnostic dye. Methylene Blue Hydrate is also a Tau aggregation inhibitor with potential applications in neurodegenerative disease research. In quality control contexts, Methylene Blue Hydrate reference standards are used for analytical method development, method validation (AMV), and ANDA applications. The hydrate form of Methylene Blue Hydrate is the standard commercial form of this compound.

 

Product Parameters

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Parameter	Specification
Product Name	Methylene Blue Hydrate
CAS Number	122965-43-9
Empirical Formula	C₁₆H20ClN₃OS
Molecular Weight	337.87 g/mol
Melting Point	190 °C
Appearance	Green crystals or crystalline powder
Storage Condition	2–8 °C

Why Cosperpharm?

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When your pharmaceutical manufacturing, quality control, or research program requires reliable Methylene Blue Hydrate, Cosperpharm delivers with the analytical rigor, documentation depth, and supply flexibility that customers demand. Methylene Blue Hydrate is a critical reagent for pharmaceutical, histological, and research applications. Our analytical release protocol includes HPLC purity verification, melting point determination (190 °C), and identity confirmation. Every shipment includes a Certificate of Analysis (COA) with batch-specific purity data and chromatographic traceability. Cosperpharm supplies Methylene Blue Hydrate across all application scales — from reference standard quantities for QC to bulk quantities for commercial manufacturing. DMF-ready documentation, stability summaries, and custom quality agreements are available upon request.

 

FAQ

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Q1: What is Methylene Blue Hydrate used for?

A: Methylene Blue Hydrate is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A), and NO synthase (NOS) inhibitor. It is used as a vasopressor agent, diagnostic dye, and research tool.

 

Q2: What is the mechanism of action of Methylene Blue Hydrate?

A: Methylene Blue Hydrate inhibits the catalytic function of inducible and constitutive nitric oxide synthases via oxidation of enzyme-bound ferrous iron.

 

 Product Quality Assurance

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Cosperpharm has established a comprehensive quality assurance system for Methylene Blue Hydrate that meets pharmaceutical and research standards:

 

Thorough analytical characterization. Each batch undergoes HPLC purity verification, melting point determination (190 °C), identity confirmation, and solubility testing.

 

Full batch traceability. Every step from raw material procurement through synthesis and final packaging is fully documented and traceable.

 

Documentation ready for regulatory submission. Every shipment includes a COA with batch-specific purity data, an SDS, and customs documentation. DMF-ready documentation packages are available upon request.

 

Customer-initiated quality audits. Qualified customers are welcome to audit Cosperpharm's facilities.

 

Contact Us

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Need a trusted partner for Methylene Blue Hydrate supply? Cosperpharm is ready to support your pharmaceutical manufacturing, quality control, or research program. Contact our team today for pricing, documentation, and technical support.