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Papaverine hydrochloride
  • Papaverine hydrochloridePapaverine hydrochloride

Papaverine hydrochloride

Model:61-25-6
Papaverine Hydrochloride (CAS 61-25-6), chemically identified as 1-(3,4-dimethoxybenzyl)-6,7-dimethoxyisoquinoline hydrochloride, is a benzylisoquinoline alkaloid originally found in opium.

Papaverine Hydrochloride is a chemical that functions as a smooth muscle relaxant, exerting its mode of action by inhibiting the enzyme phosphodiesterase and leading to an increase in intracellular levels of cyclic adenosine monophosphate (cAMP). This increase in cAMP levels results in the relaxation of smooth muscle cells, particularly those found in the blood vessels. By causing vasodilation, Papaverine Hydrochloride can increase blood flow to certain tissues and organs. Papaverine Hydrochlorides mode of action also involves its ability to directly affect the contractility of smooth muscle cells, leading to a reduction in muscle tone and relaxation of the muscle fibers. In experimental applications, Papaverine Hydrochloride is used to study the effects of smooth muscle relaxation and vasodilation on various physiological processes.

 

Product Parameters



Parameter

Specification

Product Name

Papaverine Hydrochloride

CAS Number

61-25-6

EINECS Number

200-502-1

Molecular Formula

C₂₀H₂₂ClNO₄

Molecular Weight

375.85 g/mol

Appearance

White powder

Melting Point

226 °C (dec.)

pH

3.0–4.0 (20 g/L, 25 °C)

Storage Condition

Amber vial, refrigerated



FAQ


Q1: What is the mechanism of action of Papaverine Hydrochloride?


A: Papaverine Hydrochloride functions as a smooth muscle relaxant by inhibiting the enzyme phosphodiesterase, leading to increased intracellular cAMP levels and relaxation of smooth muscle cells, particularly in blood vessels.

 

Q2: How should this compound be stored?

A: Store Papaverine Hydrochloride in an amber vial under refrigeration. The compound is light sensitive and should be protected from light.

 

Storage Conditions


Store Papaverine Hydrochloride in an amber vial under refrigeration (28 °C) in a tightly sealed container. Protect from light as the compound is light sensitive. Keep the container dry and stored in a clean, well-ventilated area away from strong oxidizing agents.


 

Shelf life: Refer to the Certificate of Analysis for batch-specific expiry date.

 

Handling precautions: Use only in a fume hood. Wear chemical-resistant gloves, safety goggles, and a lab coat. Avoid generating dust or aerosols.

 

 Application Scenarios


Smooth Muscle Relaxation Studies


Used to study the effects of smooth muscle relaxation and vasodilation on various physiological processes

 

Phosphodiesterase Inhibition Research

Serves as a tool compound for studying PDE inhibition and cAMP signaling pathways

 

Vasodilation Studies

Used to investigate cerebral vasodilation and vascular physiology

 

Calcium Channel Research

Studied for its calcium channel actions in vascular smooth muscle

 

Pharmaceutical Formulation Development

Used in the development of formulations for impotence treatment and other indications

 

Analytical Method Development

Serves as a reference standard for HPLC method development and quality control

 

Contact Us


Need Papaverine Hydrochloride for your smooth muscle research or formulation development? Cosperpharm is here to help get in touch today.


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