Products

Ceritinib (CAS 1032900-25-6) is a highly potent, orally bioavailable, ATP-competitive second-generation tyrosine kinase inhibitor that selectively targets anaplastic lymphoma kinase (ALK). Chemically, Ceritinib is a member of the class of aminopyrimidines—specifically, 2,6-diamino-5-chloropyrimidine in which the amino groups at positions 2 and 6 are respectively carrying 2-methoxy-4-(piperidin-4-yl)-5-methylphenyl and 2-(isopropylsulfonyl)phenyl substituents.

Selexipag (CAS 475086-01-2) is a potent, highly selective, and orally available non-prostanoid agonist of the prostacyclin (PGI₂) receptor (IP receptor). Chemically, Selexipag is a pyrazine derivative with the systematic name 2-(4-((5,6-diphenylpyrazin-2-yl)(isopropyl)amino)butoxy)-N-(methylsulfonyl)acetamide.

Anamorelin (CAS 249921-19-5) is a non-peptidic, orally active ghrelin mimetic and growth hormone secretagogue that functions as a highly selective agonist of the growth hormone secretagogue receptor (GHS-R1a). Structurally, Anamorelin is a complex spiroindole-piperidine compound featuring a central piperidine ring with a benzyl substituent at the 3-position, a trimethylhydrazide carboxamide functionality, and an indole-containing amino acid side chain.

Vilazodone Hydrochloride (CAS 163521-12-8) is the hydrochloride salt form of vilazodone, a small‑molecule antidepressant approved by the U.S. Food and Drug Administration for the treatment of major depressive disorder (MDD) in adults.

Tipiracil Hydrochloride (also known as TPI) is the hydrochloride salt form of tipiracil, a potent and selective inhibitor of thymidine phosphorylase (TPase, EC 2.4.2.4). Chemically designated as 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]pyrimidine-2,4(1H,3H)-dione hydrochloride, Tipiracil Hydrochloride features a pyrimidine ring fused with an imidazole and a pyrrolidine ring system.

Osimertinib Mesylate (AZD-9291 mesylate) is the mesylate salt form of osimertinib, a third-generation, orally bioavailable, irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). Chemically designated as N-(2-{[2-(dimethylamino)ethyl]methylamino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide methanesulfonate, Osimertinib Mesylate features a quinazoline core with an acrylamide warhead that forms a covalent bond with the C797 residue in the ATP-binding pocket of the EGFR kinase domain, enabling prolonged target inhibition.