Products

The product is 3',4'-Difluoroacetophenone, a 1‑(3,4‑difluorophenyl)ethan‑1‑one that features an acetyl group attached to a 1,2‑difluorinated benzene ring. The two fluorine atoms, being strongly electron‑withdrawing, deactivate the aromatic ring toward electrophilic substitution while simultaneously polarizing the carbonyl group, increasing its susceptibility to nucleophilic attack and altering the reduction potential relative to unsubstituted acetophenone. This small, densely functionalized liquid is a versatile starting material for introducing a 3,4‑difluorophenyl motif — a metabolic‑blocking strategy widely employed in medicinal chemistry — into larger frameworks via condensation, Grignard addition, or reductive amination.

tert-Butoxycarbonylamino-(4,4-difluoro-cyclohexyl)-acetic acid (also known as (S)-2-((tert-Butoxycarbonyl)amino)-2-(4,4-difluorocyclohexyl)acetic acid or Boc-S-2-(4,4-difluorocyclohexyl)glycine) is a chiral, Boc-protected amino acid derivative featuring a stereospecific (S)-configuration at the α-carbon center.

(2S)-2-amino-6-((1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethoxy)carbonylamino)hexanoic acid is a photocaged lysine derivative featuring a complex molecular architecture that combines a chiral α-amino acid core with a photolabile nitrobenzodioxole (nitropiperonyl) protecting group. The molecule consists of an L-lysine backbone with the ε-amino group masked by a (1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethoxy)carbonyl moiety.

2-Benzyloxy-3-tert-butoxycarbonylamino-propionic acid (also known as 2-(Benzyloxy)-3-[(tert-butoxycarbonyl)amino]propanoic acid) is a dual-protected β-amino acid building block belonging to the isoserine family. Structurally, the molecule features a propanoic acid backbone with an α-benzyloxy substituent and a β-Boc-protected amine.

(2S)-2-amino-2-(4,4-difluorocyclohexyl)acetic acid hydrochloride is a chiral, non-proteinogenic α-amino acid derivative featuring a gem-difluorinated cyclohexyl ring at the β-position. The molecule consists of a glycine α-carbon bearing an amino group and a carboxylic acid, with a 4,4-difluorocyclohexyl substituent attached to the α-carbon. The hydrochloride salt form protonates the amino group, enhancing aqueous solubility and improving crystallinity and handling properties.

2-((tert-Butoxycarbonyl)amino)-3,3-dicyclopropylpropanoic acid (CAS 2272861-72-8) is an N-Boc-protected amino acid derivative featuring the distinctive 3,3-dicyclopropyl-substituted alanine scaffold. The molecular structure comprises an N-terminal tert-butoxycarbonyl (Boc) protecting group, a carboxylic acid at the C-terminus, and a geminal dicyclopropyl substitution at the β-position.