Rotigotine

Rotigotine is a leading non-ergoline dopamine agonist API and reference standard in the treatment of Parkinson's disease and Restless Legs Syndrome. As a full dopamine receptor agonist with high D₃ receptor affinity, Rotigotine provides continuous dopaminergic stimulation through its unique transdermal delivery system. In quality control and regulatory contexts, Rotigotine is supplied with comprehensive characterization data compliant with regulatory guidelines, making it suitable for analytical method development, method validation (AMV), and quality control applications. The unique aminotetralin scaffold of Rotigotine continues to serve as a template for medicinal chemistry research exploring novel dopamine receptor agonists and neurological therapeutics.

Product Parameters

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Parameter	Specification
Product Name	Rotigotine
CAS Number	99755-59-6
Molecular Formula	C₁₉H₂₅NOS
Molecular Weight	315.47 g/mol
Appearance	White to off-white powder
Melting Point	470.1±45.0 ℃
Boiling Point	1.15±0.1g/cm3
Storage Condition	Room temperature

Efficacy and Effects

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Rotigotine is a non-ergot dopamine receptor agonist that stimulates dopamine receptors in the brain and is used as monotherapy for Parkinson's disease or in combination with levodopa.

 

Side effects

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Rotigatin may cause allergic reactions. Other adverse effects include dizziness, headache, sudden drowsiness, insomnia, gastrointestinal discomfort, constipation, and orthostatic hypotension.

 

Bioactivity

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Rotigotine is a dopamine receptor agonist used for the treatment of Parkinson's disease and restless legs syndrome.

 

Contact Us

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Cosperpharm is your trusted partner for Rotigotine — from analytical reference standards to commercial API supply. Contact our team today for pricing, documentation, or technical support. We respond within 2 business hours.