Avibactam Sodium (CAS 1192491-61-4) is a novel, covalent, and reversible non‑β‑lactam β‑lactamase inhibitor that restores the activity of β‑lactam antibiotics against resistant bacterial strains. The molecule features a unique diazabicyclooctane scaffold with a molecular formula of C₇H₁₀N₃NaO₆S and a molecular weight of 287.23 g/mol.
Albasvir (also known as Elbasvir, CAS 1370468-36-2) is a potent, directacting antiviral agent that inhibits the hepatitis C virus (HCV) nonstructural protein 5A (NS5A). The molecule features a complex macrocyclic structure with a molecular formula of C₄₉H₅₅N₉O₇ and a molecular weight of 882.02 g/mol.
Ramelteon (CAS 196597-26-9) is a synthetic melatonin receptor agonist featuring a unique indeno-furan bicyclic scaffold fused to a propionamide side chain. The molecule is structurally derived from the endogenous hormone melatonin, with a rigid tricyclic framework that confers high affinity and selectivity for the MT₁ and MT₂ melatonin receptors.
Dronedarone (CAS 141626-36-0) is a non‑iodinated benzofuran derivative developed as a Class III antiarrhythmic agent for the management of paroxysmal and persistent atrial fibrillation. Structurally related to amiodarone, Dronedarone differs by the absence of iodine atoms, which eliminates the iodine‑associated thyroid and pulmonary toxicities that limit amiodarone’s long‑term use.
Dronedarone Hydrochloride (CAS 141625-93-6) is the hydrochloride salt form of dronedarone, a non-iodinated benzofuran derivative developed as a Class III antiarrhythmic agent for the treatment of atrial fibrillation. Structurally related to amiodarone, Dronedarone Hydrochloride lacks the iodine moieties that are associated with amiodarone-induced thyroid and pulmonary toxicity.
Ficonalkib (CAS 2233574-95-1) is a potent, selective, third-generation inhibitor of anaplastic lymphoma kinase (ALK), a receptor tyrosine kinase implicated in various malignancies, particularly non-small cell lung cancer (NSCLC). The molecular structure of Ficonalkib (SY-3505) features a pyrrolo[2,3-d]pyrimidine core with a dimethylaminopiperidinyl substituent and a propan-2-ylsulfonylphenyl group.
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