GS-650804 / Boc-(S)-cyclopropylglycine (N-[(1,1-dimethylethoxy)carbonyl]-(S)-amino-cyclopropylacetic acid) is a Boc-protected non-natural amino acid featuring a cyclopropyl group at the α-carbon of the glycine scaffold. This unique structural motif combines the sterically constrained cyclopropyl ring with the chirality of the (S)-configuration, creating a conformationally locked amino acid analogue that is highly valued in medicinal chemistry and peptide research.
Boc-His(Trt)-Ala-OH (N-[(1,1-dimethylethoxy)carbonyl]-1-(triphenylmethyl)-L-histidyl-L-alanine) is a protected dipeptide building block featuring a Boc-protected histidine residue at the N-terminus with a trityl (Trt) group on the imidazole side chain, coupled to an alanine residue at the C-terminus.
Pal-Lys(Boc)-OH (N-[(1,1-dimethylethoxy)carbonyl]-L-lysine palmitoyl ester) is a specialized amino acid derivative featuring a lysine backbone with dual modifications: a tert-butyloxycarbonyl (Boc) protecting group on the α-amino functionality and a palmitoyl (hexadecanoyl) ester group on the side-chain carboxyl.
H-D-Lys(Boc)-NH2 (N⁶-(tert-Butoxycarbonyl)-D-lysine amide) is a single-enantiomer, orthogonally protected D-lysine derivative. With the molecular formula C₁₁H₂₃N₃O₃ and molecular weight of 245.32 g/mol, this compound features a molecular architecture consisting of a free α-amino group, a C-terminal carboxamide, and a tert-butoxycarbonyl (Boc)-protected ε-amino side chain.
Boc-Pip-OtBu (tert-butyl 4-{[(tert-butoxy)carbonyl]amino}piperidine-4-carboxylate) is a protected piperidine derivative featuring dual tert-butyl protecting groups. With the molecular formula C₁₅H₂₈N₂O₄ and molecular weight of 300.39 g/mol, this compound presents a piperidine ring with both the amine and carboxyl functionalities protected as tert-butyl carbamates and tert-butyl esters, respectively.
Boc-Alaninol (N-Boc-(S)-2-aminopropanol) is a chiral amino alcohol derived from L-alanine, featuring a tert-butyloxycarbonyl (Boc) protecting group on the amine and a free primary hydroxyl group. The molecule, with the molecular formula C₈H₁₇NO₃ and molecular weight of 175.23 g/mol, presents a well-defined (S)-configuration at the stereocenter adjacent to the amine, establishing it as an enantiopure chiral building block.
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