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Boc-Ser(tBu)-OH

Boc-Ser(tBu)-OH

Boc-Ser(tBu)-OH (N-Boc-O-tert-butyl-L-serine, CAS 13734-38-8) is a protected amino acid derivative featuring a tert-butoxycarbonyl (Boc) group protecting the α-amino functionality and a tert-butyl ether group protecting the side-chain hydroxyl of L-serine.
Boc-D-Val-OH

Boc-D-Val-OH

Boc-D-Val-OH (N-Boc-D-valine, CAS 22838-58-0) is a protected amino acid derivative featuring a tert-butoxycarbonyl (Boc) group protecting the α-amino functionality of D-valine. As the D-enantiomer of valine, Boc-D-Val-OH embodies the opposite stereochemistry at the α-carbon compared to the naturally occurring L-valine, with a specific rotation of [α]²⁰/D +5.0 to +8.0° (c=1, acetic acid).
Boc-D-Pro-OH

Boc-D-Pro-OH

Boc-D-Pro-OH (N-Boc-D-proline, CAS 37784-17-1) is a protected amino acid derivative featuring a tert-butoxycarbonyl (Boc) group protecting the secondary amine of D-proline. As a cyclic, secondary amino acid, Boc-D-Pro-OH presents unique structural characteristics that distinguish it from standard α-amino acids: the pyrrolidine ring imposes significant conformational constraints on peptide backbones, while the D-configuration provides the non-natural stereochemistry that is increasingly valued in peptide drug design.
Boc-Gln-OH

Boc-Gln-OH

Boc-Gln-OH (Nα-Boc-L-glutamine, CAS 13726-85-7) is a protected derivative of the amino acid L-glutamine, featuring a tert-butoxycarbonyl (Boc) group protecting the α-amino functionality. The molecular formula is C₁₀H₁₈N₂O₅ with a molecular weight of 246.26 g/mol. The molecule retains the carboxamide side chain of glutamine, which is crucial for hydrogen bonding and biological recognition.
Boc-Tyr-OH

Boc-Tyr-OH

Boc-Tyr-OH (N-Boc-L-tyrosine, CAS 3978-80-1) is a protected derivative of the essential amino acid L-tyrosine, featuring a tert-butoxycarbonyl (Boc) group protecting the α-amino functionality. The molecular formula is C₁₄H₁₉NO₅ with a molecular weight of 281.31 g/mol.
Boc-Glu(OMe)-OH

Boc-Glu(OMe)-OH

Boc-Glu(OMe)-OH (N-Boc-L-glutamic acid 5-methyl ester, CAS 45214-91-3) is a protected derivative of L-glutamic acid featuring a tert-butoxycarbonyl (Boc) group protecting the α-amino functionality and a methyl ester protecting the γ-carboxylic acid side chain. The molecular formula is C₁₁H₁₉NO₆ with a molecular weight of 261.27 g/mol. This orthogonal protection strategy — employing an acid-labile Boc group for the amine and a base-labile methyl ester for the side-chain carboxylate — enables selective deprotection and coupling reactions during solid-phase and solution-phase peptide synthesis.
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